Publications

2025

Saliba A, Debnath S, Tamayo I, Lee HJ, Ragi N, Das F, Montellano R, Tumova J, Maddox M, Trevino E, Singh P, Fastenau C, Maity S, Zhang G, Hejazi L, Venkatachalam MA, O'Connor JC, Fongang B, Hopp SC, Bieniek KF, Lechleiter JD, Sharma K. Quinolinic acid potentially links kidney injury to brain toxicity. JCI Insights 2025; Feb 13:e180229.

Honnorat N, Mojtabai M, Li K, Li J, Martinez DM, Rashid T, Smith M, Flanagan ME, Fadaee E, Torres MF, Keating M, Bieniek K, Seshadri S, Habes M. Multi-atlas Multi-modality Morphometry Analysis of the South Texas Alzheimer’s Disease Research Center Postmortem Repository. NeuroImage: Clinical 2025; 45:103752.

Cantu RC, Sills AK, Alosco ML, Arbogast KB, Bazarian JJ, Bieniek KF, Crandall JR, Iverson GL, Katz DI, Keene CD, Mack CD, McKee AC, Meehan WP, Mez J, Nowinski CJ, Okonkwo DO, Solomon G, Stein TD, Tartaglia MC, Zafonte RD, Daneshvar DH. Prevention of Concussion and Long-Term Effects of Repetitive Traumatic Brain Injury: Unanimous Consensus from the Cantu Concussion Summit. PM&R 2025; DOI:10.1002/pmrj.13332.

2024

Ramirez P, Sun W, Dehkordi SK, Zare H, Fongang B, Bieniek KF, Frost B. Nanopore-based DNA long-read sequencing analysis of the aged human brain. bioRxiv 2024; Feb 5:2024.02.01.578450.

Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Christopher EA, DeTure M, Seeley WW, Lee EB, Frosch MP, Molina-Porcel L, Gefen T, Redding-Ochoa J, Ghetti B, Robinson AC, Kobylecki C, Rowe JB, Beach TG, Teich AF, Keith JL, Bodi I, Halliday GM, Gearing M, Arzberger T, Morris CM, White CL III, Mechawar N, Boluda S, MacKenzie IR, McLean C, Cykowski MD, Wang S-HJ, Graff C, Nagra RM, Kovacs GG, Giaccone G, Neumann M, Ang L-C, Carvalho A, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA, Pick’s disease International Consortium. MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study. Lancet Neurology 2024; 23(5):487-499.

Fastenau C, Bunce M, Keating M, Wickline J, Hopp SC, Bieniek KF. Distinct patterns of plaque and microglia glycosylation in Alzheimer's disease. Brain Pathology 2024; 34(4):e13267.

Saliba A, Debnath S, Tamayo I, Tumova J, Maddox M, Singh P, Fastenau C, Maity S, Joo Lee H, Zhang G, Hejazi L, O'Connor J, Fongang B, Hopp SC, Bieniek KF, Lechleiter JD, Sharma K. Quinolinic acid links kidney injury to brain toxicity. bioRxiv 2024; DOI: 10.1101/2024.05.07.592801.

Honnorat N, Mojtabai M, Li J, Smith M, Seshadri S, Bieniek K, Habes M. A New Halogenated Solvent For Ex Vivo Magnetic Resonance Imaging. bioRxiv 2024; DOI: 10.1101/2024.06.05.597589.

Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross O, Murray ME, Faura J, Haggarty SJ, van Rooij JGJ, Mol MO, Hsiung G-YR, Graff C, Öijerstedt L, Neumann M, Asmann Y, McDonnel SK, Baheti S, Josephs KA, Whitwell JL, Bieniek KF, Forsberg L, Heuer H, Lago AL, Geier EG, Yokoyama JS, Oddi AP, Flanagan M, Mao Q, Hodges JR, Kwok JB, Domoto-Reilly K, Synofzik M, Wilke C, Onyike C, Dickerson BC, Evers BM, Dugger BN, Munoz DG, Keith J, Zinman L, Rogaeva E, Suh ER, Gefen T, Geula C, Weintraub S, Diehl-Schmid J, Farlow MR, Edbauer D, Woodruff BK, Caselli RJ, Donker Kaat LL, Huey ED, Reiman EM, Mead S, King A, Roeber S, Nana AL, Ertekin-Taner N, Knopman DS, Petersen RC, Petrucelli L, Uitti RJ, Wszolek ZK, Marisa Ramos E, Grinberg LT, Luisa Gorno Tempini M, Rosen HJ, Spina S, Piguet O, Grossman M, Trojanowski JQ, Keene D, Lee-Way J, Prudlo J, Geschwind DH, Rissman RA, Cruchaga C, Ghetti B, Halliday GM, Beach TG, Arzberger T, Herms J, Boxer AL, Honig LS, Vonsattel JP, Lopez OL, Kofler J, White III CL, Gearing M, Glass J, Rohrer JD, Irwin DJ, Lee EB, Van Deerlin V, Castellani R, Mesulam MM, Tartaglia MC, Finger EC, Troakes C, Al-Sarraj S, Miller BL, Seelaar H, Graff-Radford NR, Boeve BF, Mackenzie IRA, van Swieten JC, Seeley WW, Sleegers K, Dickson DW, Biernacka JM, and Rademakers R. Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole Genome Sequencing. medRxiv 2024; DOI: 10.1101/2024.06.24.24309088.

Smith MM, Ochoa E, Barannikov S, Keating M, Habes M, Flanagan ME, Seshadri S, Bieniek KF. Protocol for hybrid structured-light three-dimensional scanning and modeling of human postmortem brains. STAR Protocols 2024; 5(3):103246.

Murakami A, Koga S, Fujioka S, White AE, Bieniek KF, Sekiya H, DeJesus-Hernandez M, Finch NA, Van Blitterswijk M, Nakamura M, Tsuboi Y, Murray ME, Wszolek ZK, Dickson DW. Upper motor neuron-predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study. Brain Pathology 2024; e13286.

Xu Z, Shabestari SK, Barannikov S, Bieniek KF, Blurton-Jones M, Palavicini JP, Han X. Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer's Disease Revealed by Pharmacological and Genetic Microglial Depletion. bioRxiv 2024; DOI: 10.1101/2024.11.18.624173.

Richardson TE, Orr ME, Orr TC, Rohde SK, Ehrenberg AJ, Thorn EL, Christie TD, Flores-Almazan V, Afza R, De Sanctis C, Maldonado-Díaz C, Hiya S, Canbeldek L, Kulumani Mahadevan LS, Slocum C, Samanamud J, Clare K, Scibetta N, Yokoda RT, Koenigsberg D, Marx GA, Kauffman J, Goldstein A, Selmanovic E, Drummond E, Wisniewski T, White CL, III, Goate AM, Crary JF, Farrell K, Alosco ML, Mez J, McKee AC, Stein TD, Bieniek KF, Kautz TF, Daoud EV, Walker JM. Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer’s disease, and primary age-related tauopathy hippocampi. Alzheimer’s & Dementia 2024; 21:e14487.

2023

Ochoa E, Ramirez P, Gonzalez E, De Mange J, Ray WJ, Bieniek KF, Frost B. Pathogenic tau-induced transposable element-derived dsRNA drive neuroinflammation. Science Advances 2023; 9(1): eabq5423.

McKee AC, Stein TD, Huber BR, Crary JF, Bieniek KF, Dickson D, Alvarez VE, Cherry JD, Farrell K, Butler M, Uretsky M, Abdolmohammadi B, Alosco ML, Tripodis Y, Mez J, Daneshvar DH. Chronic Traumatic Encephalopathy (CTE): Criteria for Neuropathological Diagnosis and Relationship to Repetitive Head Impacts. Acta Neuropathologica 2023; 145(4): 371-394.

Fastenau C, Wickline JL, Smith S, Odfalk KF, Solano L, Bieniek KF, Hopp SC. Increased α-2,6 Sialic Acid on Microglia in Amyloid Pathology is Resistant to Oseltamivir. Geroscience 2023; 45(3): 1539-1555.

Beckmann A, Ramirez P, Gamez M, Gonzalez E, DeMange J, Bieniek KF, Ray WJ, Frost B.  Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer’s disease. iScience 2023; 26(3): 106152.

He S, Qiu S, Pan M, Palavicini JP, Wang H, Li X, Bhattacharjee A, Barannikov S, Bieniek KF, Dupree JL, Han X. Central nervous system sulfatide deficiency as a causal factor for bladder disorder in Alzheimer's disease. Clinical and Translational Medicine 2023; 13(7): e1332.

Li K, Rashid T, Li J, Honnorat N, Nirmala AP, Fadaee E, Wang D, Charisis S, Liu H, Franklin C, Maybrier M, Katragadda H, Abazid L, Clarke G, Maestre G, Richardson T, Walker J, Fox PT, Bieniek KF, Seshadri S, Habes M. Postmortem brain imaging in Alzheimer's Disease and related dementias: the South Texas Alzheimer's Disease research center repository. Journal of Alzheimer’s Disease 2023; 96(3):1267-128.

Hopp SC, Rogers JG, Smith S, Campos G, Miller H, Barannikov S, Kuri EG, Wang H, Han X, Bieniek KF, Weintraub SE, Palavicini JP. Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain. bioRxiv 2023; Dec 8:2023.12.06.570499.

2022

Odfalk KF, Bieniek KF, Hopp SC. Microglia: Friend and Foe in Tauopathy. Progress in Neurobiology 2022; 216:102306.

Farrell K, Iida MA, Cherry JD, Casella A, Stein TD, Bieniek KF, Walker JM, Richardson TE, White CL, Alvarez VE, Huber BR, Dickson DW, Insausti R, Dams O’Connor K, The PART working group, Crary JF, McKee AC. Differential vulnerability of hippocampal subfields in primary age-related tauopathy and chronic traumatic encephalopathy. Journal of Neuropathology and Experimental Neurology 2022; 81(10):781-789.

Cherry JD, Baucom ZH, Eppich KG, Kirsch D, Dixon ER, Tripodis Y, Bieniek KF, Farrell K, Whitney K, Uretsky M, Crary JF, Dickson D, McKee AC. Neuroimmune proteins can differentiate between tauopathies. Journal of Neuroinflammation 2022; 19(1): 278.

2021

Bieniek KF, Cairns NJ, Crary JF, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Dams-O'Connor K, Gordon WA, Tripodis Y, Alvarez VE, Mez J, Alosco ML, McKee AC and the TBI/CTE group. The second NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Journal of Neuropathology and Experimental Neurology 2021; 80(3):210-219.

Walker JM, Fudym Y, Farrell K, Iida MA, Bieniek KF, Seshadri S, White CL, Crary JF, Richardson TE. Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease. Journal of Neuropathology and Experimental Neurology 2021; 80(5):436-445.

Walker JM, Gilbert AR, Bieniek KF, Richardson TE. COVID-19 Patients with CNS Complications and Neuropathologic Features of Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalopathy. Journal of Neuropathology and Experimental Neurology 2021; 80(6):628-631.

2020

Bieniek KF, Joseph KA, Lin WL, Dickson DW. Neuronal intermediate filament inclusion disease may be incorrectly classified as a subtype of FTLD-FUS. Free Neuropathology 2020; 1:9.

McKee AC, Stein TD, Crary JF, Bieniek KF, Cantu RC, Kovacs GG. Practical considerations in the diagnosis of mild chronic traumatic encephalopathy and distinction from age-related tau astrogliopathy. Journal of Neuropathology and Experimental Neurology 2020; 79(8):921-924.

2019

Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente C, Matchett B, Karydas AM, Hsiung G-YR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL,  Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh ER, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C,  Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R. Genome-wide analyses as part of the international FTLD-TDP whole genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica 2019; 137(6):879-899.

Santos OA, Pedraza O, Lucas JA, Duara R, Greig-Custo MT, Hanna Al-Shaikh FS, Liesinger AM, Bieniek KF, Hinkle KM, Lesser ER, Crook JE, Carrasquillo MM, Ross OA, Ertekin-Taner N, Graff-Radford NR, Dickson DW, Murray ME. Ethnoracial Differences in Alzheimer’s Disease from the Florida Autopsied Multi-Ethnic Cohort. Alzheimer’s & Dementia 2019; 15(5):635-643.

Sakae N, Roemer SF, Bieniek KF, Murray ME, Baker MC, Kasanuki K, Graff-Radford NR, Petrucelli L, Van Blitterswijk M, Rademakers R, Dickson DW. Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations. Annals of Clinical and Translational Neurology 2019; 6(9):1782-1796.

Takahata K, Kimura Y, Sahara N, Koga S, Shimada H, Ichise M, Saito F, Moriguchi S, Kitamura S, Kubota M, Umeda S, Niwa F, Mizushima J, Morimoto Y, Funayama M, Tabuchi H, Bieniek KF, Kawamura K, Zhang M-R, Dickson DW, Mimura M, Suhara T, Higuchi M. PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury. Brain 2019; 142(10):3265-3279.

Bieniek KF, Blessing MM, Heckman MG, Diehl NN, Serie AM, Paolini MA, Boeve BF, Savica R, Reichard RR, Dickson DW. Association between participation in contact sports and chronic traumatic encephalopathy: a large retrospective cohort study. Brain Pathology 2019; 30(1):63-74.

2018

Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, Lopez de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sanchez-Valle R, Antonell A, Llado A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, Van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Franqipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, Van Rooij JG, Seelar H, Mead S, Caselli RJ, Reiman EM, Sabbagh MN, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Öijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, Van Swieten JC, White CL, Ghetti B, Murell JR, Mackenzie IR, Hsiung GYR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurology 2018; 17(6):548-558.

Finkel AM and Bieniek KF. A Quantitative Risk Assessment for Chronic Traumatic Encephalopathy (CTE) in Football: How Public Health Science Evaluates Evidence. Human and Ecological Risk Assessment 2018; 25(3):564-589.

Sakae N, Bieniek KF, Zhang Y-J, Ross K, Gendron TF, Murray ME, Rademakers R, Petrucelli L, Dickson DW. Poly-GR Dipeptide Repeat Polymers Correlate with Neurodegeneration and Clinicopathological Subtypes in C9ORF72-Related Brain Disease. Acta Neuropathologica Communications 2018; 6:63.

2017

Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson V, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobágyi T, Ironside JW, King A, Kofler J, Kövari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z,  Rozemüller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Thal DR, Weis S, Wharton SB, White CL III, Woulfe JM, Yamada M, Trojanowski JQ.  Multisite assessment of aging-related tau astrogliopathy (ARTAG).  Journal of Neuropathology and Experimental Neurology 2017; 76(7):605-619.

DeJesus-Hernandez M, Finch NA, Wang X, Gendron TF, Bieniek KF, Heckman MG, Vasilevich A, Murray ME, Rousseau L, Weesner R, Lucido A, Parsons M, Chew J, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Graff-Radford NR, De Boer J, Asmann YW, Petrucelli L, Boylan KB, Dickson DW, Van Blitterswijk M, and Rademakers R.  In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers.  Acta Neuropathologica 2017; 134(2):255-269.

Finch NA, Wang X, Baker MC, Heckman MG, Gendron TF, Bieniek KF, Wuu J, DeJesus-Hernandez M, Brown PH, Chew J, Jansen-West KR, Daughrity LM, Nicholson AM, Murray ME, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Petrucelli L, Boeve BF, Graff-Radford NR, Asmann YW, Dickson DW, Benatar M, Bowser R, Boylan KB, Rademakers R, Van Blitterswijk M. Abnormal expression of homeobox genes and transthyretin in C9ORF72 expansion carriers. Neurology Genetics 2017; 3(4):e161.

2016

Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobagyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL, Wisniewski T, Woulfe JM, Yamada M, Dickson DW. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica 2016; 131(1):87-102.

McKee AC, Cairns NJ, Dickson DW,  Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA, and the TBI/CTE group. The First NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy. Acta Neuropathologica 2016; 131(1):75-86.

Koga S, Dickson DW, Bieniek KF. Chronic traumatic encephalopathy pathology in multiple system atrophy. Journal of Neuropathology & Experimental Neurology 2016; 75(10):963-970.

2015

Pottier C, Bieniek KF, Finch N, Van de Vorst M, Baker M, Perkersen R, Brown P, Ravenscroft T, van Blitterswijk M, Nicholson AM, DeTure M, Knopman DS, Josephs KA, Parisi JE, Petersen R, Boylan KB, Boeve BF, Graff-Radford NR, Veltman JA,  Gilissen C, Murray M, Dickson DW, Rademakers R. Whole genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease. Acta Neuropathologica 2015; 130(1):77-92.

Nakamura M, Bieniek KF, Lin WL, Graff-Radford NR, Murray ME, Castanedes-Casey M, Desaro P, Baker MC, Rutherford NJ, Robertson J, Rademakers R, Dickson DW, Boylan KB. A truncating SOD1 mutation, p.Gly141X, is associated with clinical and pathologic heterogeneity, including frontotemporal lobar degeneration. Acta Neuropathologica 2015; 130(1):145-157.

Chew J, Gendron TF, Prudencio M, Sasaguri H, Zhang Y-J, Castanedes-Casey M, Lee CW, Jansen-West K, Kurti A, Murray ME, Bieniek KF, Bauer PO, Whitelaw EC, Rousseau L, Stankowski JN, Stetler C, Daughrity LD, Perkerson EA, Desaro P, Johnston A, Overstreet K, Edbauer D, Rademakers R, Boylan KB, Dickson DW, Fryer JD, Petrucelli L. C9ORF72 repeat expansions in mice cause c9FTD/ALS pathology, neuronal loss and behavioral deficits. Science 2015; 348(6239):1151-1154.

Prudencio M, Belzil VV, Batra R, Ross CA, Gendron TF, Pregent LJ, Murray ME, Overstreet KK, Piazza-Johnston AE, Desaro P, Bieniek KF, DeTure M, Lee WC, Biendarra SM, Davis MD, Baker MC, Perkerson RB, Van Blitterswijk M, Stetler CT, Rademakers R, Link CD, Dickson DW, Boylan KB, Li H, Petrucelli L. Distinct brain transcriptome profiles in C9ORF72-associated and sporadic ALS. Nature Neuroscience 2015; 18(8):1175-1182.

Gendron TF*, van Blitterswijk M*, Bieniek KF, Daughrity LD, Rush BK, Pedraza O, Lucas JA, Murray ME, Desaro P, Robertson A, Overstreet K, Thomas CS, Crook JE, Rademakers R, Dickson DW, Petrucelli L, Boylan KB. Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers. Acta Neuropathologica 2015; 130(4):559-73. *co-first authors

Bieniek KF, Dickson DW. Concurrent neurodegenerative pathologies in periventricular nodular heterotopia. Acta Neuropathologica 2015; 130(6):895-897.

Bieniek KF, Ross OA, Cormier KA, Walton RL, Soto-Ortolaza A, Johnston AE, DeSaro P, Boylan KB, Graff-Radford NR, Wszolek ZK, Rademakers R, Boeve BF, McKee AC, Dickson DW. Chronic Traumatic Encephalopathy Pathology in a Neurodegenerative Disorders Brain Bank. Acta Neuropathologica 2015; 130(6):877-889.

2014

Van Blitterswijk M, Mullen B, Nicholson AM, Bieniek KF, Heckman M, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PE, Murray ME, Hsiung GYR, Stewart H, Karydas AM, Finger A, Kertesz A, Bigio EH, Hatanpaa K, White CL, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R. TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathologica 2014; 127(3):397-406.

Bieniek KF, van Blitterswijk M, Baker M, Petrucelli L, Rademakers R, Dickson DW. Expanded C9ORF72 Hexanucleotide Repeat in Depressive Pseudodementia. JAMA Neurology 2014; 71(6):775-781.

Cannon A*, Bieniek KF*, Lin WL, Notari S, Zou WQ, Gambetti P, Pedraza O, Graff-Radford NR, Ferman TJ, Dickson DW. Concurrent variably protease-sensitive prionopathy and amyotrophic lateral sclerosis. Acta Neuropathologica 2014; 128(2):313–315. *co-first authors

Zhang Y-J, Jansen-West K, Xu Y-F, Gendron TF, Bieniek KF, Lin WL, Sasaguri H, Caulfield T, Hubbard J, Daughrity L, Chew J, Belzil VV, Prudencio M, Castanedes-Casey M, Whitelaw E, Ash PEA, DeTure M, Dickson DW, Petrucelli L. Aggregation-prone c9FTD/ALS poly(GA) RAN translated proteins cause neurotoxicity by inducing ER stress. Acta Neuropathologica 2014; 128(4):505-524.

2013

Bieniek KF, Murray ME, Rutherford NJ, Castanedes-Casey M, DeJesus-Hernandez M, Liesinger AM, Baker MC, Boylan KB, Rademakers R, Dickson DW. Tau Pathology in Frontotemporal Lobar Degeneration with C9ORF72 Hexanucleotide Repeat Expansion. Acta Neuropathologica 2013; 125(2):289-302.

Ash PEA*, Bieniek KF*, Gendron TF, Caulfield T, Lin WL, DeJesus-Hernandez M, van Blitterswijk M, Jansen-West K, Paul JW, Rademakers R, Boylan KB, Dickson DW, Petrucelli L. Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS. Neuron 2013; 77(4):639-646. *co-first authors

Boeve BF, Molano JR, Ferman TJ, Lin SC, Bieniek K, Tippmann-Peikert M, Petersen RC, Boot B, St. Louis E, Silber MH. Validation of the Mayo Sleep Questionnaire to Screen for REM Sleep Behavior Disorder in a Community-Based Sample. Journal of Clinical Sleep Medicine 2013; 9(5):475-480.

Van Blitterswijk M, Baker MC, Bieniek KF, Knopman DS, Josephs KA, Boeve B, Caselli R, Wszolek ZK, Petersen R, Graff-Radford NR, Boylan KB, Dickson DW, Rademakers R. Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2013; 14(5-6):463-469.

Murray ME, Bieniek KF, Greenberg MB, DeJesus-Hernandez M, Rutherford NJ, Ash PEA, Gendron TF, Kouri N, Baker M, Goodman IJ, Petrucelli L, Rademakers R, Dickson DW. Progressive Amnestic Dementia, Hippocampal Sclerosis, and Mutation in C9orf72. Acta Neuropathologica 2013; 126(4):545-554.

Van Blitterswijk M, Baker MC, DeJesus-Hernandez M, Ghidoni R, Benussi L, Finger E, Hsiung GYR, Kelley B, Murray ME, Rutherford NJ, Brown PE, Ravenscroft T, Mullan B, Ash PEA, Bieniek KF, Hatanpaa KJ, Karydas A, McCarty-Wood E, Coppola G, Bigio EH, Lippa C, Strong MJ, Beach TG, Knopman DS, Huey ED, Mesulam M, Bird T, White CL, Kertesz A, Geschwind DH, Van Deerlin VM, Petersen RC, Binetti G, Miller BL, Petrucelli L, Wszolek ZK, Boylan KB, Graff-Radford NR, Mackenzie IR, Boeve BF, Dickson DW, Rademakers R. C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology 2013; 81(15):1332-1341.

Gendron TF*, Bieniek KF*, Zhang Y-J, Jansen-West K, Ash PEA, Caulfield T, Daughrity L, Dunmore J, Castanedes-Casey M, Chew J , Cosio DM, van Blitterswijk M, Lee WC, Rademakers R, Boylan KB, Dickson DW, Petrucelli L. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Acta Neuropathologica 2013; 126(6):829-844. *co-first authors

McDade EM, Boot BP, Christianson TJH, Pankratz VS, Boeve BF, Ferman TJ, Bieniek K, Hollman JH, Roberts RO, Mielke MM, Knopman DS, Petersen RC. Subtle gait changes in patients with REM sleep behavior disorder. Movement Disorders 2013; 28(13):1847-1853.

2011

Boeve BF, Molano JR, Ferman TJ, Smith GE, Lin SC, Bieniek K, Haidar W, Tippmann-Peikert M, Knopman D, Graff-Radford N, Lucas JA, Petersen RC, Silber MH. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in an aging and dementia cohort. Sleep Medicine 2011; 12(5):445-453.